PCNA mAb
|
货号 |
P01L084 |
|
规格 |
100uL |
|
种属反应性 |
H,R,Dog,Bovine,Dog, Chicken, Monkey |
|
应用 |
WB, IP, FC |
|
宿主 |
Rabbit |
|
说明书下载 |
|
Background
Proliferating cell nuclear antigen(PCNA) Homosapiens： The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome.
