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一抗系列
P02A100 BAX mAb
发布时间:2019-12-19 13:55 来源:市场部
BAX mAb

货号 P02A100
规格 20ul/50ul/100ul
种属反应性 Human,Rat,Mouse
应用 WB, IHC-P,IP, FC
宿主 Rabbit
说明书下载
P02A100说明书


Background

         The protein encoded by BAX (BCL2 associated X, apoptosis regulator) belongs to the BCL2 protein family. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis.